SCION SQ GC-MS, SCION Instruments, UK
The SCION (SQ) GC-MS is designed for today’s fast paced analytical laboratory. Innovative design features such as a Lens-Free ion path, heated ion optics and an Extended Dynamic Range (EDR) detector enable the SCION SQ to deliver accurate quantification and identification on a routine basis, even in complex matrices. As ions pass through a mass spectrometer a significant portion is lost every time they encounter a lens. Due to its unique design the SCION SQ doesn’t have any lenses thus increasing the sensitivity of the instrument by reducing ion losses. Another major advantage of having no lenses the source is the only part to clean, so you can spend more time analysing samples and less time maintaining your instrument. The SQ is integrated with our SCION 436 or 456 GC as sole or as additional detector.
Regardless of sample type or throughput, SCION GC-MS’s can provide an automated solution to meet your requirements. Two SCION sampler options are available, the 8400 and 8410. Each can be tailored to meet specific sampling needs and workloads. Third party samplers like TELEDYNE TEKMAR Versa head-space sampler and CTC PAL-xt systems are easily integrated.
How the SCION GC-MS can work for the Chemical market
SCION can provide GC-MS systems, custom and standard, following standardised industry methods and approaches to ensure both, agreement with their clients on product specification and quality of results. High availability of the whole infrastructure with a 24/7 uptime, high end-to-end redundancy as well as high-level automation is a key requirement that can be achieved best with help of our GC/MS solutions dedicated to this type of industry.
How the SCION GC-MS can work for the Pharmaceutical market
SCION’s SQ GC-MS combines highest sensitivity with a maximum of sample throughput and lowest down time which is a key requirement for Pharma where it can be used in analytical research in the initial research process of new drug screening, during the subsequent process of chemical/biological synthesis, the routine quality control and quality assurance of bulk drugs, formulations, manufactured drugs and packing materials, the characterization and quantification of impurities in drug components (impurity profiling), and the quantification of the active ingredient (API) and its metabolized degradation products in non-clinical pharmacokinetic studies. Besides support of the multi-stage pharmaceutical process of drug development, synthesis and production SCION’s SQ GC-MS finds its place also in many fields of medicine, like clinical toxicology and drug abuse, or newborn screening tests for inborn error of metabolism just to name some fields where sensitivity, reliability and maximum uptime plays a significant role.
How the SCION GC-MS can work for the Environmental market
SCION has a range of dedicated GC-MS solutions specifically designed to monitor different environmental contaminants. Combining pre-concentration techniques and specific detection allow for the sub ppb level determinations required. From headspace VOC analysis of water to pre-configured GC-MS systems for pesticide residue and SVOC identification we can provide you with the best solution for even the most demanding applications.
How the SCION GC-MS can work for the Food market
SCION has a range of dedicated GC-MS solutions specifically designed for the food industry. Combining pre-concentration techniques and specific detection allow for trace level determinations. From headspace systems to pre-configured, custom analysers we can provide you with the best solution for even the most demanding applications.
The SCION SQ is the chromatographer’s choice for quadrupole mass detector; it is designed to match your most stringent needs for analytical performance and productivity. The SCION SQ offers superior sensitivity and robustness based on innovative ion optics, and fast and easy methods development. The SCION SQ GC-MS system defines a new standard of usability for routine analysis. Analyser – MS Specifications • Scan modes: Full Scan; Selected Ion Monitoring (SIM), Combined Full Scan-SIM • Standard ionization mode: Electron Ionisation (EI) • Optional ionization modes: Chemical Ionisation (CI) including PCI and NCI • Ion source: Auto-aligning EI or CI (optional) sources constructed of inert materials • Q0 ion guide: 90° curved RF-only entrance quadrupole with active ion beam focusing • Source temperature: 100°C to 350°C • Filament and emission cur r ent: dual filaments; up to 200μA • Electron energy: adjustable from 10 to 150eV • Mass filter: quadrupole with pre- and post-filter; high ion transmission efficiency lens-less design • Mass range (m/z): 1 to 1200 Da • Scan rate: up to 20,000Da/sec • Minimum dwell times: 1ms • Resolution: user adjustable from Unit (0.7Da) to 4Da, also with three user selectable settings (Unit, Standard, Open) • Mass axis stability:
Gas Chromatograph (SCION 436 and 456 Model GC) For more specification on GC refer to the GC Data Sheet • Injectors: Split/Splitless (SSL), Programmable Temperature Vaporisation (PTV) and PTV with back-flush (PTV/BF), Coldon-Column (COC) • Autosamplers: CP 8400; CP 8410; CTC PAL COMBI-xt • GC Oven Temperature: Ambient+10°C (436 Model) or +4°C (456 Model) to 450°C, -100°C to 450°C (with Liquid N2, 456 Model); -60°C to 450°C (with Liquid CO2, 456 Model) • Temperature Ramps/Holds: 24/25 (Model 436); 24/25 (Model 456) • Pneumatic: Electronic Flow Control (EFC) or Manual • ChromatoProbe: Direct introduction of solids, liquids or slurries (requires PTV injector) Performance Specifications* * All tests performed with helium at carrier gas † The Signal-to-Noise ratio S/N values are based on RMS Δ CI tests use methane as reagent gas Dimensions (H x W x D) and Weight Additional spaces should be added for the data system, monitor and printer • SCION SQ: 45cm (18in) x 28cm (11in) x 57cm (22.5in), 37kg/82lb • 436GC: 57cm (23.6in) x 32cm (13in) x 61cm (24in); 27kg/59lb • 456GC: 57cm (22.5in) x 66cm (26in) x 56cm (22in); 43kg/95lb • CP-8400/8410 Autosamplers: 22cm (8.5in) x 40cm (15.7in) x 47cm (18.5in); 7kg/15.3lb Mode Test (with SSL injector in hot splitless mode) Specification † EI Full Scan S/N ≥1500:1 PCI Full Scan S/N ≥600:1 NCI Full Scan 1pg Octafluoronaphthalene (OFN) from m/ z50 to 300 for m/z272 100pg Benzophenone (BZP) from m/z80 to 230 for m/z183 200fg OFN from m/z200 to 300 for m/z272 S/N ≥1000:1