Moxifloxacin

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Moxifloxacin

Moxifloxacin Hydrochloride Moxifloxacin Hcl BP EP USP

Synonyms: Moxifloxacine Hydrochloride Moxifloxacine Hcl

CAS Number: 186826-86-8

Moxifloxacin Hydrochloride Monohydrate CAS 192927-63-2

Characteristics: Slightly yellow to yellow crystalline powder, mp 324-325°

Molecular Formula: C21H25ClFN3O4

Structure Formula:

image002

Package: 25Kgs/Fiber Drum

KEY Words:

Moxifloxacin Hydrochloride Moxifloxacin Hcl BP EP USP

Description:

The indications of Moxifloxacin Hydrochloride Moxifloxacin Hcl BP EP USP are for adults with upper and lower respiratory tract infections (18 years old at least), such as acute sinusitis, acute episodes of chronic bronchitis, community acquired pneumonia, and skin and soft tissue infections.

Moxifloxacin Hydrochloride Moxifloxacin Hcl BP EP USP is a broad-spectrum and antimicrobial agent of 8-methoxyfluoroquinolones.

This substance shows broad-spectrum antimicrobial activity against Gram-positive bacteria, gram-negative bacteria, anaerobic bacteria, acid-fast bacteria and atypical microorganisms such as Mycoplasma, Chlamydia and Legionella.

However, when taking Moxifloxacin Hydrochloride Moxifloxacin Hcl BP EP USP, we should pay attention to the use of quinolones which can induce epilepsy. For patients with known or suspected central nervous system diseases that may lead to epilepsy or reduce the seizure threshold, we should pay attention to the use of quinolones.

Moxifloxacin Hydrochloride Moxifloxacin Hcl BP EP USP is a fluoroquinolone antibiotic. Its mechanism of action and in vitro antimicrobial spectrum are similar to those of other fluoroquinolones, but its antimicrobial activity to Gram-positive bacteria and anaerobic bacteria is similar to that of trovafloxacin, which is superior to some old varieties. Compared with other fluoroquinolones, the drug-resistant Gram-positive bacteria produced little or very slowly. Cross-resistant bacteria were found among Gram-negative bacteria and enterococci and other fluoroquinolones.

Synthesis Method of Moxifloxacin Hydrochloride Moxifloxacin Hcl BP EP USP:

image003

image004

Other Names:

(1’S,6’S)-1-cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-(1,4-dihydroquinoline)-3-carboxylic acid hydrochloride salt; 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo-[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid hydrochloride; 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydropyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride; Moxifloxacin (Hydrochloride); MoxifloxacineHCl;

Others related products

Macrolides: Azithromycin, clarithromycin, roxithromycin
Quinolones: Ciprofloxacin hydrochloride, ciprofloxacin lactate, ciprofloxacin, ciprofloxacin mesylate, moxifloxacin
Special APIs: Azrendipine, fudosten, mitiglinide, desoxyfluridine, solifenacin, vildagliptin
Veterinary APIs: Ciprofloxacin hydrochloride, enrofloxacin, marbofloxacin, diclazuril, ciprofloxacin
Key pharmaceutical intermediates: Dihydrohomoerythromycin, erythromycin oxime, cyclopropanecarboxylic acid

Supplier in Bangladesh- Elite Scientific & Meditech Co.

Others Link of elitetradebd

Ciprofloxacin lactate

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Ciprofloxacin Lactate

Name: Ciprofloxacin Lactate
CAS NO.:97867-33-9
Formula:C17H18FN3O3.C3H6O3

Synonyms:Ciprofloxacinum Lactate, Ciprofloxacine Lactate

CAS Number:97867-33-9

Characteristics: Almost white or light yellow crystalline powder

Molecular Formula:C20H22FN3O5; C17H18FN3O3.C3H6O3

Structure Formula:

image002

Package: 25Kgs/Fiber Drum

KEY Words:Ciprofloxacin Lactate raw material

Description:

Ciprofloxacin Lactate raw material is an antibacterial drug. It is used for genitourinary infection caused by sensitive bacteria, including simple and complex urinary tract infection, bacterial prostatitis, Neisseria gonorrhoeae urethritis or cervicitis (including enzyme producing strains

Cause). Ciprofloxacin Lactatecan also treat respiratory tract infection, including acute attack of bronchial infection caused by sensitive gram-negative bacilli and pulmonary infection. Treatment of gastrointestinal infection by Shigella, Salmonella, enterotoxin producing Escherichia coli, Aeromonas hydrophila, Vibrio parahaemolyticus, etc. It can also be used to treat typhoid, bone and joint infection, skin and soft tissue infection, septicemia and other systemic infections.

Ciprofloxacin Lactate raw material is soluble in water, slightly soluble in methanol, almost insoluble in ethanol, ethyl acetate, petroleum ether or dioxane.

Functions and applications:

The antibacterial spectrum of Ciprofloxacin Lactate is similar to that of norfloxacin. It has strong antibacterial activity against Gram-positive bacteria, Gram-negative bacteria, Pseudomonas aeruginosa and anaerobic bacteria. For sensitive bacteria caused by systemic infection and Mycoplasma (Mycoplasma) infection.

The new broad-spectrum antibiotics, Ciprofloxacin Lactatehas strong permeability, high blood concentration, low toxicity, are not easy to produce drug resistance, and can be quickly distributed to other organs. The medicine is easy to absorb by oral administration, and the effect of intramuscular injection is better. New quinolones

Broad spectrum antibiotics like Ciprofloxacin Lactatehave a strong effect on Gram-positive and Gram-negative bacteria. Fengchen Group is a leading China Ciprofloxacin Lactate Powder supplier and manufacturer. We specialize in wholesale and bulk amounts, ensuring all our clients have the right ChinaCiprofloxacin Lactate powder manufacturer and supplier when they need it. When you are going to buy or purchase Ciprofloxacin Lactate Powder from China, please turn to Fengchen Group.

Other applications:
  1. Ciprofloxacin Lactatecan be used for Urogenital system infection, including simple and complex urinary tract infection, bacterial prostatitis, Neisseria gonorrhoeae urethritis or cervicitis (including those caused by enzyme producing strains).
  2. It can also be utilized to fight against Respiratory tract infection, including acute attack of bronchial infection caused by sensitive gram-negative bacilli and pulmonary infection.
  3. Ciprofloxacin Lactateis also very useful for treating Gastrointestinal infection is caused by Shigella, Salmonella, enterotoxin producing Escherichia coli, Aeromonas hydrophila, Vibrio parahaemolyticus, etc.
  4. Typhoid fever.
  5. Bone and joint infection.
  6. Skin and soft tissue infection.
  7. Systemic infection such as septicemia.
Certificate of Analysis (COA, TDS)
Name of Product Ciprofloxacin Lactate
Testing Item Standard Result
Appearance Almost white or light yellow crystalline powder; Odorless and bitter, hygroscopicity Complies
Identification A Bismuth potassium Iodide solution test: Solution shows brownish red. Complies
Identification B UV: Absorption max at 277nm Complies
Identification C IR: Conforms to the reference spectrum Complies
Identification D Lactate Test: Positive Complies
pH 4.5 ~ 5.5 4.9
Clarity of solution Clear Clear
Color of solution Absorption at 430nm ≤0.05 0.03
Fluoride ≥ 4.2% 4.5%
Related Substances Individual Impurity ≤0.5%

Total Impurities ≤1.0%

< 0.5%

< 1.0%

Loss on drying (60 °C) ≤ 6.5% 4.4%
Residual on Ignition ≤0.1% 0.08%
Heavy Metal ≤20ppm <20ppm
Assay ≥ 98.5% on dried basis 98.9%
Others related products

Macrolides: Azithromycin, clarithromycin, roxithromycin
Quinolones: Ciprofloxacin hydrochloride, ciprofloxacin lactate, ciprofloxacin, ciprofloxacin mesylate, moxifloxacin
Special APIs: Azrendipine, fudosten, mitiglinide, desoxyfluridine, solifenacin, vildagliptin
Veterinary APIs: Ciprofloxacin hydrochloride, enrofloxacin, marbofloxacin, diclazuril, ciprofloxacin
Key pharmaceutical intermediates: Dihydrohomoerythromycin, erythromycin oxime, cyclopropanecarboxylic acid

Supplier in Bangladesh- Elite Scientific & Meditech Co.

Others Link of elitetradebd

Roxithromycin

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Roxithromycin

Product Name: Roxithromycin, Roxithromicin Powder API, Raw Material BP, EP, USP

Synonyms: Roxithromycine; Roxithromycinum

CAS Number: 80214-83-1

Characteristics: White or almost white crystalline powder

Assay:  96.0% ~ 102.0% Roxithromycin

Formula: C41H76N2O15

Structure Formula:

Package information:  25Kg/Fiber Drum, Cardboard Drum, Paper Drum

KEY Words: Roxithromycin, Roxithromicin Powder API, Raw Material BP, EP, USP

Description and Usage:
Roxithromycin is an antibiotic. It has an immunomodulatory effect. Roxithromycin is known to be  a wide antibacterial spectrum against oral pathogens.
Roxithromycin can also increase neutrophil apoptosis. It is semisynthetic Erythromycin derivative. Antibacterial.
While Roxithromycin is active against a wide spectrum of pathogens, it is particularly effective in the treatment of respiratory and genital tract infections. It is a semi-synthetic macrolide anti-biotic (similar antimicrobial spectrum as erythromycin).
Roxithromycin prevents bacteria from growing, by interfering with their proteinynthesis.
Roxithromycin is very effective against certain gram-negative bacteria.

Roxithromycin is a semi-synthetic macrolide antibiotic. It is very similar in composition, chemical structure and mechanism of action to erythromycin, azithromycin, or clarithromycin. Roxithromycin prevents bacteria from growing, by interfering with their protein synthesis. Roxithromycin binds to the subunit 50S of the bacterial ribosome, and thus inhibits the translocation of peptides. Roxithromycin has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila. It can treat respiratory tract, urinary and soft tissue infections. It is not available in the United States, but is available in Australia.

Roxithromycin belongs to a group of medicines called macrolide antibiotics.

It is used for the treatment of the following infections:

– Respiratory infections from both upper and lower airways, such as otitis, sinusitis, pharyngitis, tonsillitis, bronchitis and pneumonia..
– Skin and soft tissue infections.
– Urinary tract infections.

As a professional China Roxithromycin Powder API, Raw Material BP, EP, USP supplier and Manufacturer in China, FENGCHEN GROUP CO., LTD has been supplying and exporting Roxithromycin Powder API, Raw Material BP, EP, USP from China in China for almost 10 years.

Caution: Do not use roxithromycin there is following conditions If you are allergic (hypersensitive) to roxithromycin.

Allergy symptoms may include:

– Asthma attacks with shortness of breath, audible wheezing or rapid breathing.
– More or less sudden swelling of face, lips, tongue or elsewhere in the body. It is especially critical if it affects the vocal cords.
– Hives, itching, rash
– Anaphylactic shock (loss of consciousness, paleness, sweating, etc.).

Nor you should take this medicine:

If you are being treated with rye ergot alkaloids.

COA of Roxithromycin :
Testing Item Standard Result
Appearance
Roxithromycin
White or almost white crystalline powder Complies
Solubility: Roxithromycin is very slightly soluble in water, freely soluble in acetone, in alcohol and in methylene chloride. It is slightly soluble in dilute hydrochloric acid Positive
Identification 1: IR: Conforms to the Roxithromycin CRS Spectrum Complies
Identification 2:
Roxithromycin
HPLC: Similar inretention time and size to the principal peak of reference solution (a) Complies
Appearance of solution: Clear and colorless Clear and colorless
Specific Optical Rotation -93° ~ -96° -95°
Impurity G ≤  1.0% 0.19%
Impurity A,B,C,D,E,F,H,I,J ≤  0.5% 0.32%
Total Impurities ≤  3.0% 1.9%
Heavy Metal ≤  10ppm 10ppm
Water ≤  3.0% 1.9%
Sulphated Ash ≤  0.1% 0.01%
Residual on Ignition ≤  0.1% 0.05%
Methanol ≤  3000ppm 589ppm
Acetone ≤  5000ppm 47ppm
Methylene Chloride ≤  600ppm Not Detected
Assay Roxithromycin 96.0% ~ 102.0% 98.9%
Others related products

Macrolides: Azithromycin, clarithromycin, roxithromycin
Quinolones: Ciprofloxacin hydrochloride, ciprofloxacin lactate, ciprofloxacin, ciprofloxacin mesylate, moxifloxacin
Special APIs: Azrendipine, fudosten, mitiglinide, desoxyfluridine, solifenacin, vildagliptin
Veterinary APIs: Ciprofloxacin hydrochloride, enrofloxacin, marbofloxacin, diclazuril, ciprofloxacin
Key pharmaceutical intermediates: Dihydrohomoerythromycin, erythromycin oxime, cyclopropanecarboxylic acid

Supplier in Bangladesh- Elite Scientific & Meditech Co.

Others Link of elitetradebd

Clarithromycin

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Clarithromycin

Name: Clarithromycin
Molecular formula: C38H69NO
CAS NO.: 81103-11-9

Synonyms: Clarithromycine; Clathromycin, Clarithromycinum

Chemical name: 6-O-Methylerythromycin.

Forms: Clarithromycin Granular, Clarithromycin Granule; Clarithromycin Micronized Powder, Clarithromycin Micro Powder

Characteristics: White to off-white crystalline powder.

Assay: 94% Min

Formula: C38H69NO13

Structure Formula:

Fosfomycin Phenylethylamine Powder Raw Material, API BP, EP, USP structure.png

Density: 1.18 g/cm3

Melting Range: 217-220ºC

Package information: 25Kgs/Drum;  5KG/Drum, 10KG/Drum

KEY Words: Clarithromycin, Clarithromycine, Clarithromycinum Powder API, Raw Material

Storage: Store only in original container. Keep container tightly closed.

Quality standard: CP/  USP/  IP2014

Description: 

Clarithromycin is a semisynthetic macrolide anti-biotic. It derives from erythromycin.

Clarithromycin will inhibit bacteria’s protein synthesis. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation.

Clarithromycin is an antibiotic used to treat various bacterial infections. For example the infections of  includes strep throat, pneumonia, skin, H. pylori infection, and Lyme disease. Clarithromycin can be taken orally as a pill or liquid.

Developed in 1980. Clarithromycin is on the WHO’s List of Essential Medicines, it is the most important medications needed in a basic health system. Clarithromycin is available as a generic medication. Clarithromycin is made from erythromycin, and it have a chemical name 6-O-methylerythromycin.

Clarithromycin Powder API, Raw Material is a semi-synthetic macrolide antibiotic, which is chemically related to erythromycin and azithromycin. Clarithromycin is effective against a wide variety of bacteria, such as Haemophilus influenzae, mycobacterium avium, Streptococcus pneumoniae, etc. Like all macrolide antibiotics, Clarithromycin Powder API, Raw Material will interfere bacteria’s ability to make proteins, thus the growth will be stopped. Due to the differences in the way proteins are made in bacteria and humans, Clarithromycin will not interfere with production of proteins in humans. Clarithromycin Powder API, Raw Material derived from Streptomyces bacteria. It will inhibit protein synthesis by bacteria at the 50S ribosome. They are characterized by a macrocyclic ring (a large ring molecule with many functional groups bonded to it) and a large lactone ring in the molecular structure. Clarithromycin is usually used to produce medicines which is indicated for tract, skin, and genitourinary infections.

Clarithromycin Inhibits Myometrial Contractions in Isolated Human Myometrium Independent of Stimulus.

Classification:

Clarithromycin Powder API, Raw Material will be classified as Antibacterial, Antibiotic, Anti-infective Agent, Gastrointestinal Agent, Macrolide.

As a professional China Clarithromycin Powder API, Raw Material supplier and Manufacturer in China, FENGCHEN GROUP CO., LTD has been supplying and exporting Clarithromycin Powder API, Raw Material from China in China for almost 10 years.

Side effects: 

There may be nausea, vomiting, headaches, and diarrhea. Severe allergic reactions are very rare. It may cause harm if taken during pregnancy.

The mechanism of action of Clarithromycin: 

Clarithromycin is an Inhibitor. It is in the macrolide class and works by stopping the making of protein by some bacteria.

 The chemical classification of Clarithromycin is Macrolides.

Application:

Clarithromycin is used to treatment of pharyngitis and tonsillitis caused by Streptococcus pyogenes, Acute otitis media, pneumonia and bronchitis caused by Streptococcus pneumoniae, Bronchitis and mycoplasma pneumonia caused by Haemophilus influenza and catarrh, skin and soft tissue infections caused by Staphylococcus and streptococcus.

-Clarithromycin can made into oral tablets or capsules. There are immediate-release form and an extended-release form.

-Clarithromycin may also be made into oral suspension.

Certificate of Analysis of Clarithromycin

Items Specifications Results
Appearance

Clarithromycin

White to almost white crystalline powder white crystalline powder
Solubility

Clarithromycin

Soluble in acetone;slightly soluble in

dehydrated alcohol, in methanol,

and in acctonitrile,and in phosphate butter at

PH values of 2 to5;

practically insoluble in water

Conforms
Identification

Clarithromycin

IR:conforms to the spectrum of clarithromycin RS Conforms
Specific optical  rotation -94.–102.(anhydrous substance,1

0mg/ml methylene chloride)

-98.
Sulphated ash ≤ 0.2% <0.01%
Appearance of solution Clear or not more opalescent than reference

suspension II and not more intensely coloured than reference solutionY7

Conforms
Crystallinity Meet the requirements Conforms
pH 8.0-10.0 8.7
Water ≤ 2.0% 0.35%
Related substances (1)any single impurity ≤ 1.0% 0.65%
(2)any impurities

greater than 0.4%

not more than 4 impurities 1
(3)total impurities ≤ 3.5% 2.0%
Heavy metals ≤ 0.002% 2.0%
Residul solvents Ethanol ≤ 5000ppm Not detected
Pyridine≤220ppm Not detected
Assay (on dried basis )

Clarithromycin

96.0% ~ 102.0%(anhydrous substance) 97.3%
Conclusion It complies with USP38 standard.

Other Names:

Biaxin; Clathromycin; Claritromicina; Claritromicina; 6-O-Methylerythromycin; 6-O-Methylerythromycin A; Clarithromycine; Clarithromycinum; (3R,4S,5S,6R,7R,9R,11S,12R,13S,14S)-6-([(2S,3R,4S,6R)-4-(dimethylamino)- 3-hydroxy-6- methyloxan -2-yl]oxy) -14-ethyl-12,13-dihydroxy-4-(((2R,4S,5S,6S)-5-hydroxy -4-methoxy- 4,6- dimethyloxan-2-yl)oxy)-7 -methoxy-3,5,7,9 ,11,13-hexamethyl -1-oxacyclotetradecane -2,10-dione

Related Products

Macrolides: Azithromycin, clarithromycin, roxithromycin
Quinolones: Ciprofloxacin hydrochloride, ciprofloxacin lactate, ciprofloxacin, ciprofloxacin mesylate, moxifloxacin
Special APIs: Azrendipine, fudosten, mitiglinide, desoxyfluridine, solifenacin, vildagliptin
Veterinary APIs: Ciprofloxacin hydrochloride, enrofloxacin, marbofloxacin, diclazuril, ciprofloxacin
Key pharmaceutical intermediates: Dihydrohomoerythromycin, erythromycin oxime, cyclopropanecarboxylic acid

Ciprofloxacin HCL

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Ciprofloxacin Base CAS 85721-33-1, Ciprofloxacin Lactate CAS 97867-33-9, 
Ciprofloxacin Hydrochloride or Hcl CAS 86483-48-9, Ciprofloxacin HCL
Product   Name: Ciprofloxacin Base API, Raw Material Ciprofloxacin Lactate API, Raw Material Ciprofloxacin Hydrochloride API, Raw Material
Synonyms: Cipfloxacine,

Ciprofloxacini

Ciprofloxacini Lactate Ciprofloxacin Hcl,

Ciprofloxacini hydrochloridum

CAS: 85721-33-1 97867-33-9 86483-48-9

or 86393-32-0

Appearance: White   crystalline powder White   powder or crystalline powder A   pale yellow, crystalline powder, soluble in water
Assay: 98.0%-102.0% 98.5%   Min 98%  ~ 102%
Formula: C17H18FN3O3 C20H22FN3O5 C17H18FN3O3,HCl,H2O
Structure:
Package: 25Kg/Fiber Drum, Cardboard Drum, Paper Drum

Description:

Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride are both slats of Ciprofloxacin. They are all broad-spectrum antimicrobial carboxyfluoroquinolines. They belong to fluoroquinolone class.  Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride have bactericidal ability because they will inhibit enzymes topoisomerase II (DNA gyrase) and topoisomerase IV. There 2 enzymes needed in many bacterial DNA processes, like replication, transcription, repair, strand supercoiling repair, and recombination.

Ciprofloxacin Lactate, Ciprofloxacin Hcl are applied to treat many bacterial-caused infections such as  lung or respiratory tract infections, eye infection, bladder and kidney infections, reproductive tract infections, skin and soft tissue infections and bone and joint infections.

Till now, there is still no cross-resistance between ciprofloxacin and other classes of antimicrobials known to us. We should note that Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride have 100 times higher affinity for bacterial DNA gyrase than for mammalian.

As a professional China Cipfloxacin Base,  Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride Raw Material API supplier and Manufacturer, FENGCHEN GROUP CO., LTD has been supplying and exporting Cipfloxacin Base,  Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride Raw Material API from China for almost 10 years.

Mechanism of Action:

The way of action of Cipfloxacin Base,  Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride is different from that of other antimicrobial agents like beta-lactams, macrolides, tetracyclines, or aminoglycosides; That is to say, organisms which are resistant to these drugs are still ciprofloxacin. Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride will still work to them.

Absorption of Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride:

Ciprofloxacin will be  absorbed from the gastrointestinal tract after oral administration very quickly. The absolute bioavailability is approximately seventy percents with no substantial loss by first pass metabolism.

COA—Ciprofloxacin Base

Name of Product Ciprofloxacin base
Testing   Item Standard Result
Appearance

Ciprofloxacin base

White crystalline powder
White   Crystalline Powder
Clarity of solution

Ciprofloxacin base

Meet the requirements Meets the requirements
Loss on drying ≤1.0% 0.2%
Residue on ignition ≤0.2% 0.12%
Heavy metals ≤0.002% ≤0.002%
Sulfate

Chloride

≤0.04%

≤0.04%

<0.04%

<0.02%

Fluoroquinolonic acid Meet the requirements Meets the requirements
Ciprofloxacin ethylenediamine anlog ≤0.2% 0.05%
Any other individual impurity ≤0.2% 0.03%
Total impurities ≤0.5% 0.14%
Assay (on the anhydrous basis) 98.0%-102.0%

Ciprofloxacin Base

100.9%

COA—Ciprofloxacin Lactate

Name   of Product Ciprofloxacin Lactate
Testing Item Standard Result
Appearance

Ciprofloxacin Lactate

Almost   white or light yellow crystalline powder; Odorless and bitter, hygroscopicity Complies
Identification A Bismuth potassium Iodide solution   test: Solution shows brownish red. Complies
Identification B

Ciprofloxacin Lactate

UV: Absorption max at 277nm Complies
Identification C IR: Conforms to the reference spectrum Complies
Identification D

Ciprofloxacin Lactate

Lactate Test: Positive Complies
pH 4.5   ~ 5.5 4.9
Clarity of solution Clear Clear
Color   of solution Absorption   at 430nm ≤0.05 0.03
Fluoride ≥   4.2% 4.5%
Related   Substances Individual   Impurity ≤0.5%

Total   Impurities ≤1.0%

<   0.5%

<   1.0%

Loss   on drying (60 °C) ≤   6.5% 4.4%
Residual on Ignition ≤   0.1% 0.08%
Heavy   Metal ≤   20ppm <   20ppm
Assay   (Ciprofloxacin Lactate) ≥   98.5% on dried basis 98.9%

COA—Ciprofloxacin Hydrochloride (Ciprofloxacin Hcl)

Name   of Product Ciprofloxacin Hcl or Ciprofloxacin Hydrochloride
Testing Item Standard Result
Characters

Ciprofloxacin Hcl

Faintly   yellowish to light yellow crystals Complies
Identification   A IR   Spectrum of sample complies with the reference standard Complies
Identification   B

Ciprofloxacin Hcl

HPLC:   The retention time of the major peak of the sample solution corresponds to   the one of standard solution, as obtained in the assay Complies
Identification   C Show   reaction of chlorides. Complies
pH 3.0   ~ 4.5 3.7
Water 4.7%   ~ 6.7% 5.3%
Residue   on ignition ≤   0.1% 0.05%
Heavy   metals ≤   20ppm  Ciprofloxacin Hydrochloride <   20ppm
sulfate ≤   0.04% <   0.04%
Fluoroquinolonic   acid ≤   0.2% Complies
Ciprofloxacin   ethylenediamine ≤   0.2% 0.04%
Any   other individual impurity ≤   0.2% 0.05%
Total   impurities ≤   0.5% 0.18%
Ethanol ≤   4000ppm 426ppm
Isoamyl   Alcohol ≤   4000ppm Not   detected
Assay   (on the anhydrous basis) 98.0%   ~ 102.0%

Ciprofloxacin Hydrochloride (Ciprofloxacin Hcl)

99.4%

Related products

Macrolides: Azithromycin, clarithromycin, roxithromycin
Quinolones: Ciprofloxacin hydrochloride, ciprofloxacin lactate, ciprofloxacin, ciprofloxacin mesylate, moxifloxacin
Special APIs: Azrendipine, fudosten, mitiglinide, desoxyfluridine, solifenacin, vildagliptin
Veterinary APIs: Ciprofloxacin hydrochloride, enrofloxacin, marbofloxacin, diclazuril, ciprofloxacin
Key pharmaceutical intermediates: Dihydrohomoerythromycin, erythromycin oxime, cyclopropanecarboxylic acid

Supplier in Bangladesh- Elite Scientific & Meditech Co.

Others Link of elitetradebd

Azithromycin

$0.00
Pure Azithromycin Dihydrate Powder USP BP EP CAS 117772-70-0

Product Name: Azithromycin

Synonyms:  Azithromycin Dihydrate, Azithromycin Powder, Azithromycin Micronized

CAS Number: 117772-70-0

Characteristics: White powder.

Molecular Formula: C38H76N2O14

Structure Formula:

Azithromycin CAS 117772-70-0 structure formula

Package: 25Kgs/Fiber Drum

Assay:  945-1030μg /mg

Formula: C38H72N2O12·2H2O

Description:

Azithromycin Dihydrate belongs to the class of drugs known as macrolide antibiotics. It will kill bacteria or prevent their growth. However, Azithromycin will not work for colds, flu, or other virus infections. Azithromycin powder or injection may be used for other problems as determined by your doctor. Similar in structure to erythromycin. azithromycin reaches higher intracellular concentrations than erythromycin, increasing its efficacy and duration of action.

Mechanism of Action:

Azithromycin works by interfering with bacterial protein synthesis, thus preventing them from growing.

Like other macrolide antibiotics, Azithromycin powder raw material inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of the bacterial 70S ribosome. Azithromycin API will inhibit peptidyl transferase activity and interfere with amino acid translocation during the process of translation. Its effects may be bacteriostatic or bactericidal depending of the organism and the drug concentration. Its long half life, which enables once daily dosing and shorter administration durations, is a property distinct from other macrolides.

Fengchen Group is a leading supplier of Azithromycin Dihydrate Powder API from China. We specialize in wholesale and bulk amounts, ensuring all our clients have the right supplier of Triethylenediamine powder when they need it. When you are going to buy or purchase Azithromycin Dihydrate Raw Material, please turn to Fengchen Group.

Usage: Azithromycin (Azithromycin Dihydrate, Azithromycin Powder) is mainly used to fight bacterial infections. It is a kind of antibiotic. Azithromycin can be made into oral or other forms of pharmaceutical preparations.

Azithromycin is used to treat a vast variety of bacterial infections, especially in those with weak immune systems patients. For example, children.

Azithromycin raw material API is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections,ear infections, and sexually transmitted diseases.

Azithromycin Tablets are a macrolide antibacterial drug indicated for the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below.

NOTE:

You should not use Azithromycin if you have ever had jaundice or liver problems when you have previously taken this medicine.

Please do careful before using Azithromycin Dihydrate, Azithromycin Powder liver or kidney disease, a history of Long QT syndrome, a heart rhythm disorder.

Side Effects:

Upon taking Azithromycin, a minority of individuals are susceptible to nausea, diarrhea or vomiting.

Name of Product Azithromycin
Testing   Item Standard Result
Appearance A white or almost white crystalline   power, odorless and bitter Complies
Identification

1.        IR

2.        HPLC

1.        Conforms   to the reference spectrum

2.        Similar   in retention time to the principle peak in the chromatogram obtained with the   reference solution

Complies

 

Complies

Crystalline Should conforms to requirements Complies
Specific optical rotation -45°~    -49° -47°
Water 4.0%-5.0% 4.3%
Residue on ignition ≤0.3% 0.02%
Residue solvents 1.Methylene chloride ≤0.06%

2.Acetone ≤0.5%

1. Not detected

2. 0.1%

Heavy metals ≤0.0025% <0.0025%
PH 9.0-11.0 9.9
Assay (Azithromycin) 945-1030μg /mg 962μg /mg
Supplier Elite Scientific & Meditech Co www.elitetradebd.com

Related products

Macrolides: Azithromycin, clarithromycin, roxithromycin
Quinolones: Ciprofloxacin hydrochloride, ciprofloxacin lactate, ciprofloxacin, ciprofloxacin mesylate, moxifloxacin
Special APIs: Azrendipine, fudosten, mitiglinide, desoxyfluridine, solifenacin, vildagliptin
Veterinary APIs: Ciprofloxacin hydrochloride, enrofloxacin, marbofloxacin, diclazuril, ciprofloxacin
Key pharmaceutical intermediates: Dihydrohomoerythromycin, erythromycin oxime, cyclopropanecarboxylic acid

Supplier in Bangladesh- Elite Scientific & Meditech Co.

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