Moxifloxacin
$0.00
Moxifloxacin
Moxifloxacin Hydrochloride Moxifloxacin Hcl BP EP USP
Synonyms: Moxifloxacine Hydrochloride Moxifloxacine Hcl
CAS Number: 186826-86-8
Moxifloxacin Hydrochloride Monohydrate CAS 192927-63-2
Characteristics: Slightly yellow to yellow crystalline powder, mp 324-325°
Molecular Formula: C21H25ClFN3O4
Structure Formula:
Package: 25Kgs/Fiber Drum
KEY Words:
Moxifloxacin Hydrochloride Moxifloxacin Hcl BP EP USP
Description:
The indications of Moxifloxacin Hydrochloride Moxifloxacin Hcl BP EP USP are for adults with upper and lower respiratory tract infections (18 years old at least), such as acute sinusitis, acute episodes of chronic bronchitis, community acquired pneumonia, and skin and soft tissue infections.
Moxifloxacin Hydrochloride Moxifloxacin Hcl BP EP USP is a broad-spectrum and antimicrobial agent of 8-methoxyfluoroquinolones.
This substance shows broad-spectrum antimicrobial activity against Gram-positive bacteria, gram-negative bacteria, anaerobic bacteria, acid-fast bacteria and atypical microorganisms such as Mycoplasma, Chlamydia and Legionella.
However, when taking Moxifloxacin Hydrochloride Moxifloxacin Hcl BP EP USP, we should pay attention to the use of quinolones which can induce epilepsy. For patients with known or suspected central nervous system diseases that may lead to epilepsy or reduce the seizure threshold, we should pay attention to the use of quinolones.
Moxifloxacin Hydrochloride Moxifloxacin Hcl BP EP USP is a fluoroquinolone antibiotic. Its mechanism of action and in vitro antimicrobial spectrum are similar to those of other fluoroquinolones, but its antimicrobial activity to Gram-positive bacteria and anaerobic bacteria is similar to that of trovafloxacin, which is superior to some old varieties. Compared with other fluoroquinolones, the drug-resistant Gram-positive bacteria produced little or very slowly. Cross-resistant bacteria were found among Gram-negative bacteria and enterococci and other fluoroquinolones.
Synthesis Method of Moxifloxacin Hydrochloride Moxifloxacin Hcl BP EP USP:
Other Names:
(1’S,6’S)-1-cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-(1,4-dihydroquinoline)-3-carboxylic acid hydrochloride salt; 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo-[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid hydrochloride; 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydropyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride; Moxifloxacin (Hydrochloride); MoxifloxacineHCl;
Others related products
Macrolides: Azithromycin, clarithromycin, roxithromycin
Quinolones: Ciprofloxacin hydrochloride, ciprofloxacin lactate, ciprofloxacin, ciprofloxacin mesylate, moxifloxacin
Special APIs: Azrendipine, fudosten, mitiglinide, desoxyfluridine, solifenacin, vildagliptin
Veterinary APIs: Ciprofloxacin hydrochloride, enrofloxacin, marbofloxacin, diclazuril, ciprofloxacin
Key pharmaceutical intermediates: Dihydrohomoerythromycin, erythromycin oxime, cyclopropanecarboxylic acid
Supplier in Bangladesh- Elite Scientific & Meditech Co.
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Categories: Pharmaceuticals Raw Materials
Ciprofloxacin lactate
$0.00
Ciprofloxacin Lactate
Name: Ciprofloxacin Lactate
CAS NO.:97867-33-9
Formula：C17H18FN3O3.C3H6O3
Synonyms:Ciprofloxacinum Lactate, Ciprofloxacine Lactate
CAS Number:97867-33-9
Characteristics: Almost white or light yellow crystalline powder
Molecular Formula:C20H22FN3O5; C17H18FN3O3.C3H6O3
Structure Formula:
Package: 25Kgs/Fiber Drum
KEY Words:Ciprofloxacin Lactate raw material
Description:
Ciprofloxacin Lactate raw material is an antibacterial drug. It is used for genitourinary infection caused by sensitive bacteria, including simple and complex urinary tract infection, bacterial prostatitis, Neisseria gonorrhoeae urethritis or cervicitis (including enzyme producing strains
Cause). Ciprofloxacin Lactatecan also treat respiratory tract infection, including acute attack of bronchial infection caused by sensitive gram-negative bacilli and pulmonary infection. Treatment of gastrointestinal infection by Shigella, Salmonella, enterotoxin producing Escherichia coli, Aeromonas hydrophila, Vibrio parahaemolyticus, etc. It can also be used to treat typhoid, bone and joint infection, skin and soft tissue infection, septicemia and other systemic infections.
Ciprofloxacin Lactate raw material is soluble in water, slightly soluble in methanol, almost insoluble in ethanol, ethyl acetate, petroleum ether or dioxane.
Functions and applications:
The antibacterial spectrum of Ciprofloxacin Lactate is similar to that of norfloxacin. It has strong antibacterial activity against Gram-positive bacteria, Gram-negative bacteria, Pseudomonas aeruginosa and anaerobic bacteria. For sensitive bacteria caused by systemic infection and Mycoplasma (Mycoplasma) infection.
The new broad-spectrum antibiotics, Ciprofloxacin Lactatehas strong permeability, high blood concentration, low toxicity, are not easy to produce drug resistance, and can be quickly distributed to other organs. The medicine is easy to absorb by oral administration, and the effect of intramuscular injection is better. New quinolones
Broad spectrum antibiotics like Ciprofloxacin Lactatehave a strong effect on Gram-positive and Gram-negative bacteria. Fengchen Group is a leading China Ciprofloxacin Lactate Powder supplier and manufacturer. We specialize in wholesale and bulk amounts, ensuring all our clients have the right ChinaCiprofloxacin Lactate powder manufacturer and supplier when they need it. When you are going to buy or purchase Ciprofloxacin Lactate Powder from China, please turn to Fengchen Group.
Other applications:
- Ciprofloxacin Lactatecan be used for Urogenital system infection, including simple and complex urinary tract infection, bacterial prostatitis, Neisseria gonorrhoeae urethritis or cervicitis (including those caused by enzyme producing strains).
- It can also be utilized to fight against Respiratory tract infection, including acute attack of bronchial infection caused by sensitive gram-negative bacilli and pulmonary infection.
- Ciprofloxacin Lactateis also very useful for treating Gastrointestinal infection is caused by Shigella, Salmonella, enterotoxin producing Escherichia coli, Aeromonas hydrophila, Vibrio parahaemolyticus, etc.
- Typhoid fever.
- Bone and joint infection.
- Skin and soft tissue infection.
- Systemic infection such as septicemia.
Certificate of Analysis (COA, TDS)
| Name of Product | Ciprofloxacin Lactate | |
| Testing Item | Standard | Result |
| Appearance | Almost white or light yellow crystalline powder; Odorless and bitter, hygroscopicity | Complies |
| Identification A | Bismuth potassium Iodide solution test: Solution shows brownish red. | Complies |
| Identification B | UV: Absorption max at 277nm | Complies |
| Identification C | IR: Conforms to the reference spectrum | Complies |
| Identification D | Lactate Test: Positive | Complies |
| pH | 4.5 ~ 5.5 | 4.9 |
| Clarity of solution | Clear | Clear |
| Color of solution | Absorption at 430nm ≤0.05 | 0.03 |
| Fluoride | ≥ 4.2% | 4.5% |
| Related Substances | Individual Impurity ≤0.5%
Total Impurities ≤1.0% |
< 0.5%
< 1.0% |
| Loss on drying (60 °C) | ≤ 6.5% | 4.4% |
| Residual on Ignition | ≤0.1% | 0.08% |
| Heavy Metal | ≤20ppm | <20ppm |
| Assay | ≥ 98.5% on dried basis | 98.9% |
Others related products
Macrolides: Azithromycin, clarithromycin, roxithromycin
Quinolones: Ciprofloxacin hydrochloride, ciprofloxacin lactate, ciprofloxacin, ciprofloxacin mesylate, moxifloxacin
Special APIs: Azrendipine, fudosten, mitiglinide, desoxyfluridine, solifenacin, vildagliptin
Veterinary APIs: Ciprofloxacin hydrochloride, enrofloxacin, marbofloxacin, diclazuril, ciprofloxacin
Key pharmaceutical intermediates: Dihydrohomoerythromycin, erythromycin oxime, cyclopropanecarboxylic acid
Supplier in Bangladesh- Elite Scientific & Meditech Co.
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Categories: Pharmaceuticals Raw Materials
Roxithromycin
$0.00
Roxithromycin
Product Name: Roxithromycin, Roxithromicin Powder API, Raw Material BP, EP, USP
Synonyms: Roxithromycine; Roxithromycinum
CAS Number: 80214-83-1
Characteristics: White or almost white crystalline powder
Assay: 96.0% ~ 102.0% Roxithromycin
Formula: C41H76N2O15
Structure Formula:
Package information: 25Kg/Fiber Drum, Cardboard Drum, Paper Drum
KEY Words: Roxithromycin, Roxithromicin Powder API, Raw Material BP, EP, USP
Description and Usage:
Roxithromycin is an antibiotic. It has an immunomodulatory effect. Roxithromycin is known to be a wide antibacterial spectrum against oral pathogens.
Roxithromycin can also increase neutrophil apoptosis. It is semisynthetic Erythromycin derivative. Antibacterial.
While Roxithromycin is active against a wide spectrum of pathogens, it is particularly effective in the treatment of respiratory and genital tract infections. It is a semi-synthetic macrolide anti-biotic (similar antimicrobial spectrum as erythromycin).
Roxithromycin prevents bacteria from growing, by interfering with their proteinynthesis.
Roxithromycin is very effective against certain gram-negative bacteria.
Roxithromycin is a semi-synthetic macrolide antibiotic. It is very similar in composition, chemical structure and mechanism of action to erythromycin, azithromycin, or clarithromycin. Roxithromycin prevents bacteria from growing, by interfering with their protein synthesis. Roxithromycin binds to the subunit 50S of the bacterial ribosome, and thus inhibits the translocation of peptides. Roxithromycin has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila. It can treat respiratory tract, urinary and soft tissue infections. It is not available in the United States, but is available in Australia.
Roxithromycin belongs to a group of medicines called macrolide antibiotics.
It is used for the treatment of the following infections:
– Respiratory infections from both upper and lower airways, such as otitis, sinusitis, pharyngitis, tonsillitis, bronchitis and pneumonia..
– Skin and soft tissue infections.
– Urinary tract infections.
As a professional China Roxithromycin Powder API, Raw Material BP, EP, USP supplier and Manufacturer in China, FENGCHEN GROUP CO., LTD has been supplying and exporting Roxithromycin Powder API, Raw Material BP, EP, USP from China in China for almost 10 years.
Caution: Do not use roxithromycin there is following conditions If you are allergic (hypersensitive) to roxithromycin.
Allergy symptoms may include:
– Asthma attacks with shortness of breath, audible wheezing or rapid breathing.
– More or less sudden swelling of face, lips, tongue or elsewhere in the body. It is especially critical if it affects the vocal cords.
– Hives, itching, rash
– Anaphylactic shock (loss of consciousness, paleness, sweating, etc.).
Nor you should take this medicine:
If you are being treated with rye ergot alkaloids.
COA of Roxithromycin :
| Testing Item | Standard | Result |
| Appearance Roxithromycin |
White or almost white crystalline powder | Complies |
| Solubility: | Roxithromycin is very slightly soluble in water, freely soluble in acetone, in alcohol and in methylene chloride. It is slightly soluble in dilute hydrochloric acid | Positive |
| Identification 1: | IR: Conforms to the Roxithromycin CRS Spectrum | Complies |
| Identification 2: Roxithromycin |
HPLC: Similar inretention time and size to the principal peak of reference solution (a) | Complies |
| Appearance of solution: | Clear and colorless | Clear and colorless |
| Specific Optical Rotation | -93° ~ -96° | -95° |
| Impurity G | ≤ 1.0% | 0.19% |
| Impurity A,B,C,D,E,F,H,I,J | ≤ 0.5% | 0.32% |
| Total Impurities | ≤ 3.0% | 1.9% |
| Heavy Metal | ≤ 10ppm | 10ppm |
| Water | ≤ 3.0% | 1.9% |
| Sulphated Ash | ≤ 0.1% | 0.01% |
| Residual on Ignition | ≤ 0.1% | 0.05% |
| Methanol | ≤ 3000ppm | 589ppm |
| Acetone | ≤ 5000ppm | 47ppm |
| Methylene Chloride | ≤ 600ppm | Not Detected |
| Assay Roxithromycin | 96.0% ~ 102.0% | 98.9% |
Others related products
Macrolides: Azithromycin, clarithromycin, roxithromycin
Quinolones: Ciprofloxacin hydrochloride, ciprofloxacin lactate, ciprofloxacin, ciprofloxacin mesylate, moxifloxacin
Special APIs: Azrendipine, fudosten, mitiglinide, desoxyfluridine, solifenacin, vildagliptin
Veterinary APIs: Ciprofloxacin hydrochloride, enrofloxacin, marbofloxacin, diclazuril, ciprofloxacin
Key pharmaceutical intermediates: Dihydrohomoerythromycin, erythromycin oxime, cyclopropanecarboxylic acid
Supplier in Bangladesh- Elite Scientific & Meditech Co.
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Categories: Pharmaceuticals Raw Materials
Clarithromycin
$0.00
Clarithromycin
Name: Clarithromycin
Molecular formula: C38H69NO
CAS NO.: 81103-11-9
Synonyms: Clarithromycine; Clathromycin, Clarithromycinum
Chemical name: 6-O-Methylerythromycin.
Forms: Clarithromycin Granular, Clarithromycin Granule; Clarithromycin Micronized Powder, Clarithromycin Micro Powder
Characteristics: White to off-white crystalline powder.
Assay: 94% Min
Formula: C38H69NO13
Structure Formula:
Density: 1.18 g/cm3
Melting Range: 217-220ºC
Package information: 25Kgs/Drum; 5KG/Drum, 10KG/Drum
KEY Words: Clarithromycin, Clarithromycine, Clarithromycinum Powder API, Raw Material
Storage: Store only in original container. Keep container tightly closed.
Quality standard: CP/ USP/ IP2014
Description:
Clarithromycin is a semisynthetic macrolide anti-biotic. It derives from erythromycin.
Clarithromycin will inhibit bacteria’s protein synthesis. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation.
Clarithromycin is an antibiotic used to treat various bacterial infections. For example the infections of includes strep throat, pneumonia, skin, H. pylori infection, and Lyme disease. Clarithromycin can be taken orally as a pill or liquid.
Developed in 1980. Clarithromycin is on the WHO’s List of Essential Medicines, it is the most important medications needed in a basic health system. Clarithromycin is available as a generic medication. Clarithromycin is made from erythromycin, and it have a chemical name 6-O-methylerythromycin.
Clarithromycin Powder API, Raw Material is a semi-synthetic macrolide antibiotic, which is chemically related to erythromycin and azithromycin. Clarithromycin is effective against a wide variety of bacteria, such as Haemophilus influenzae, mycobacterium avium, Streptococcus pneumoniae, etc. Like all macrolide antibiotics, Clarithromycin Powder API, Raw Material will interfere bacteria’s ability to make proteins, thus the growth will be stopped. Due to the differences in the way proteins are made in bacteria and humans, Clarithromycin will not interfere with production of proteins in humans. Clarithromycin Powder API, Raw Material derived from Streptomyces bacteria. It will inhibit protein synthesis by bacteria at the 50S ribosome. They are characterized by a macrocyclic ring (a large ring molecule with many functional groups bonded to it) and a large lactone ring in the molecular structure. Clarithromycin is usually used to produce medicines which is indicated for tract, skin, and genitourinary infections.
Clarithromycin Inhibits Myometrial Contractions in Isolated Human Myometrium Independent of Stimulus.
Classification:
Clarithromycin Powder API, Raw Material will be classified as Antibacterial, Antibiotic, Anti-infective Agent, Gastrointestinal Agent, Macrolide.
As a professional China Clarithromycin Powder API, Raw Material supplier and Manufacturer in China, FENGCHEN GROUP CO., LTD has been supplying and exporting Clarithromycin Powder API, Raw Material from China in China for almost 10 years.
Side effects:
There may be nausea, vomiting, headaches, and diarrhea. Severe allergic reactions are very rare. It may cause harm if taken during pregnancy.
The mechanism of action of Clarithromycin:
Clarithromycin is an Inhibitor. It is in the macrolide class and works by stopping the making of protein by some bacteria.
The chemical classification of Clarithromycin is Macrolides.
Application:
Clarithromycin is used to treatment of pharyngitis and tonsillitis caused by Streptococcus pyogenes, Acute otitis media, pneumonia and bronchitis caused by Streptococcus pneumoniae, Bronchitis and mycoplasma pneumonia caused by Haemophilus influenza and catarrh, skin and soft tissue infections caused by Staphylococcus and streptococcus.
-Clarithromycin can made into oral tablets or capsules. There are immediate-release form and an extended-release form.
-Clarithromycin may also be made into oral suspension.
Certificate of Analysis of Clarithromycin
| Items | Specifications | Results | |
| Appearance
Clarithromycin |
White to almost white crystalline powder | white crystalline powder | |
| Solubility
Clarithromycin |
Soluble in acetone;slightly soluble in
dehydrated alcohol, in methanol, and in acctonitrile,and in phosphate butter at PH values of 2 to5; practically insoluble in water |
Conforms | |
| Identification
Clarithromycin |
IR:conforms to the spectrum of clarithromycin RS | Conforms | |
| Specific optical rotation | -94.–102.(anhydrous substance,1
0mg/ml methylene chloride) |
-98. | |
| Sulphated ash | ≤ 0.2% | <0.01% | |
| Appearance of solution | Clear or not more opalescent than reference
suspension II and not more intensely coloured than reference solutionY7 |
Conforms | |
| Crystallinity | Meet the requirements | Conforms | |
| pH | 8.0-10.0 | 8.7 | |
| Water | ≤ 2.0% | 0.35% | |
| Related substances | (1)any single impurity | ≤ 1.0% | 0.65% |
| (2)any impurities
greater than 0.4% |
not more than 4 impurities | 1 | |
| (3)total impurities | ≤ 3.5% | 2.0% | |
| Heavy metals | ≤ 0.002% | 2.0% | |
| Residul solvents | Ethanol ≤ 5000ppm | Not detected | |
| Pyridine≤220ppm | Not detected | ||
| Assay (on dried basis )
Clarithromycin |
96.0% ~ 102.0%(anhydrous substance) | 97.3% | |
| Conclusion | It complies with USP38 standard. | ||
Other Names:
Biaxin; Clathromycin; Claritromicina; Claritromicina; 6-O-Methylerythromycin; 6-O-Methylerythromycin A; Clarithromycine; Clarithromycinum; (3R,4S,5S,6R,7R,9R,11S,12R,13S,14S)-6-([(2S,3R,4S,6R)-4-(dimethylamino)- 3-hydroxy-6- methyloxan -2-yl]oxy) -14-ethyl-12,13-dihydroxy-4-(((2R,4S,5S,6S)-5-hydroxy -4-methoxy- 4,6- dimethyloxan-2-yl)oxy)-7 -methoxy-3,5,7,9 ,11,13-hexamethyl -1-oxacyclotetradecane -2,10-dione
Related Products
Macrolides: Azithromycin, clarithromycin, roxithromycin
Quinolones: Ciprofloxacin hydrochloride, ciprofloxacin lactate, ciprofloxacin, ciprofloxacin mesylate, moxifloxacin
Special APIs: Azrendipine, fudosten, mitiglinide, desoxyfluridine, solifenacin, vildagliptin
Veterinary APIs: Ciprofloxacin hydrochloride, enrofloxacin, marbofloxacin, diclazuril, ciprofloxacin
Key pharmaceutical intermediates: Dihydrohomoerythromycin, erythromycin oxime, cyclopropanecarboxylic acid
Categories: Pharmaceuticals Raw Materials
Ciprofloxacin HCL
$0.00
Ciprofloxacin Base CAS 85721-33-1, Ciprofloxacin Lactate CAS 97867-33-9, Ciprofloxacin Hydrochloride or Hcl CAS 86483-48-9, Ciprofloxacin HCL
| Product Name: | Ciprofloxacin Base API, Raw Material | Ciprofloxacin Lactate API, Raw Material | Ciprofloxacin Hydrochloride API, Raw Material |
| Synonyms: | Cipfloxacine,
Ciprofloxacini |
Ciprofloxacini Lactate | Ciprofloxacin Hcl,
Ciprofloxacini hydrochloridum |
| CAS: | 85721-33-1 | 97867-33-9 | 86483-48-9
or 86393-32-0 |
| Appearance: | White crystalline powder | White powder or crystalline powder | A pale yellow, crystalline powder, soluble in water |
| Assay: | 98.0%-102.0% | 98.5% Min | 98% ~ 102% |
| Formula: | C17H18FN3O3 | C20H22FN3O5 | C17H18FN3O3,HCl,H2O |
| Structure: | |||
| Package: | 25Kg/Fiber Drum, Cardboard Drum, Paper Drum | ||
Description:
Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride are both slats of Ciprofloxacin. They are all broad-spectrum antimicrobial carboxyfluoroquinolines. They belong to fluoroquinolone class. Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride have bactericidal ability because they will inhibit enzymes topoisomerase II (DNA gyrase) and topoisomerase IV. There 2 enzymes needed in many bacterial DNA processes, like replication, transcription, repair, strand supercoiling repair, and recombination.
Ciprofloxacin Lactate, Ciprofloxacin Hcl are applied to treat many bacterial-caused infections such as lung or respiratory tract infections, eye infection, bladder and kidney infections, reproductive tract infections, skin and soft tissue infections and bone and joint infections.
Till now, there is still no cross-resistance between ciprofloxacin and other classes of antimicrobials known to us. We should note that Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride have 100 times higher affinity for bacterial DNA gyrase than for mammalian.
As a professional China Cipfloxacin Base, Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride Raw Material API supplier and Manufacturer, FENGCHEN GROUP CO., LTD has been supplying and exporting Cipfloxacin Base, Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride Raw Material API from China for almost 10 years.
Mechanism of Action:
The way of action of Cipfloxacin Base, Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride is different from that of other antimicrobial agents like beta-lactams, macrolides, tetracyclines, or aminoglycosides; That is to say, organisms which are resistant to these drugs are still ciprofloxacin. Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride will still work to them.
Absorption of Ciprofloxacin Lactate, Ciprofloxacin Hydrochloride:
Ciprofloxacin will be absorbed from the gastrointestinal tract after oral administration very quickly. The absolute bioavailability is approximately seventy percents with no substantial loss by first pass metabolism.
COA—Ciprofloxacin Base
| Name of Product | Ciprofloxacin base | |
| Testing Item | Standard | Result |
| Appearance
Ciprofloxacin base |
White crystalline powder |
White Crystalline Powder |
| Clarity of solution
Ciprofloxacin base |
Meet the requirements | Meets the requirements |
| Loss on drying | ≤1.0% | 0.2% |
| Residue on ignition | ≤0.2% | 0.12% |
| Heavy metals | ≤0.002% | ≤0.002% |
| Sulfate
Chloride |
≤0.04%
≤0.04% |
＜0.04%
<0.02% |
| Fluoroquinolonic acid | Meet the requirements | Meets the requirements |
| Ciprofloxacin ethylenediamine anlog | ≤0.2% | 0.05% |
| Any other individual impurity | ≤0.2% | 0.03% |
| Total impurities | ≤0.5% | 0.14% |
| Assay (on the anhydrous basis) | 98.0%-102.0%
Ciprofloxacin Base |
100.9% |
COA—Ciprofloxacin Lactate
| Name of Product | Ciprofloxacin Lactate | |
| Testing Item | Standard | Result |
| Appearance
Ciprofloxacin Lactate |
Almost white or light yellow crystalline powder; Odorless and bitter, hygroscopicity | Complies |
| Identification A | Bismuth potassium Iodide solution test: Solution shows brownish red. | Complies |
| Identification B
Ciprofloxacin Lactate |
UV: Absorption max at 277nm | Complies |
| Identification C | IR: Conforms to the reference spectrum | Complies |
| Identification D
Ciprofloxacin Lactate |
Lactate Test: Positive | Complies |
| pH | 4.5 ~ 5.5 | 4.9 |
| Clarity of solution | Clear | Clear |
| Color of solution | Absorption at 430nm ≤0.05 | 0.03 |
| Fluoride | ≥ 4.2% | 4.5% |
| Related Substances | Individual Impurity ≤0.5%
Total Impurities ≤1.0% |
< 0.5%
< 1.0% |
| Loss on drying (60 °C) | ≤ 6.5% | 4.4% |
| Residual on Ignition | ≤ 0.1% | 0.08% |
| Heavy Metal | ≤ 20ppm | < 20ppm |
| Assay (Ciprofloxacin Lactate) | ≥ 98.5% on dried basis | 98.9% |
COA—Ciprofloxacin Hydrochloride (Ciprofloxacin Hcl)
| Name of Product | Ciprofloxacin Hcl or Ciprofloxacin Hydrochloride | |
| Testing Item | Standard | Result |
| Characters
Ciprofloxacin Hcl |
Faintly yellowish to light yellow crystals | Complies |
| Identification A | IR Spectrum of sample complies with the reference standard | Complies |
| Identification B
Ciprofloxacin Hcl |
HPLC: The retention time of the major peak of the sample solution corresponds to the one of standard solution, as obtained in the assay | Complies |
| Identification C | Show reaction of chlorides. | Complies |
| pH | 3.0 ~ 4.5 | 3.7 |
| Water | 4.7% ~ 6.7% | 5.3% |
| Residue on ignition | ≤ 0.1% | 0.05% |
| Heavy metals | ≤ 20ppm Ciprofloxacin Hydrochloride | < 20ppm |
| sulfate | ≤ 0.04% | < 0.04% |
| Fluoroquinolonic acid | ≤ 0.2% | Complies |
| Ciprofloxacin ethylenediamine | ≤ 0.2% | 0.04% |
| Any other individual impurity | ≤ 0.2% | 0.05% |
| Total impurities | ≤ 0.5% | 0.18% |
| Ethanol | ≤ 4000ppm | 426ppm |
| Isoamyl Alcohol | ≤ 4000ppm | Not detected |
| Assay (on the anhydrous basis) | 98.0% ~ 102.0%
Ciprofloxacin Hydrochloride (Ciprofloxacin Hcl) |
99.4% |
Related products
Macrolides: Azithromycin, clarithromycin, roxithromycin
Quinolones: Ciprofloxacin hydrochloride, ciprofloxacin lactate, ciprofloxacin, ciprofloxacin mesylate, moxifloxacin
Special APIs: Azrendipine, fudosten, mitiglinide, desoxyfluridine, solifenacin, vildagliptin
Veterinary APIs: Ciprofloxacin hydrochloride, enrofloxacin, marbofloxacin, diclazuril, ciprofloxacin
Key pharmaceutical intermediates: Dihydrohomoerythromycin, erythromycin oxime, cyclopropanecarboxylic acid
Supplier in Bangladesh- Elite Scientific & Meditech Co.
Others Link of elitetradebd
-
- Web address : www.elitetradebd.com
- Twitter : https://twitter.com/elitetradebd
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Categories: Pharmaceuticals Raw Materials
Azithromycin
$0.00
Pure Azithromycin Dihydrate Powder USP BP EP CAS 117772-70-0
Product Name: Azithromycin
Synonyms: Azithromycin Dihydrate, Azithromycin Powder, Azithromycin Micronized
CAS Number: 117772-70-0
Characteristics: White powder.
Molecular Formula: C38H76N2O14
Structure Formula:
Package: 25Kgs/Fiber Drum
Assay: 945-1030μg /mg
Formula: C38H72N2O12·2H2O
Description:
Azithromycin Dihydrate belongs to the class of drugs known as macrolide antibiotics. It will kill bacteria or prevent their growth. However, Azithromycin will not work for colds, flu, or other virus infections. Azithromycin powder or injection may be used for other problems as determined by your doctor. Similar in structure to erythromycin. azithromycin reaches higher intracellular concentrations than erythromycin, increasing its efficacy and duration of action.
Mechanism of Action:
Azithromycin works by interfering with bacterial protein synthesis, thus preventing them from growing.
Like other macrolide antibiotics, Azithromycin powder raw material inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of the bacterial 70S ribosome. Azithromycin API will inhibit peptidyl transferase activity and interfere with amino acid translocation during the process of translation. Its effects may be bacteriostatic or bactericidal depending of the organism and the drug concentration. Its long half life, which enables once daily dosing and shorter administration durations, is a property distinct from other macrolides.
Fengchen Group is a leading supplier of Azithromycin Dihydrate Powder API from China. We specialize in wholesale and bulk amounts, ensuring all our clients have the right supplier of Triethylenediamine powder when they need it. When you are going to buy or purchase Azithromycin Dihydrate Raw Material, please turn to Fengchen Group.
Usage: Azithromycin (Azithromycin Dihydrate, Azithromycin Powder) is mainly used to fight bacterial infections. It is a kind of antibiotic. Azithromycin can be made into oral or other forms of pharmaceutical preparations.
Azithromycin is used to treat a vast variety of bacterial infections, especially in those with weak immune systems patients. For example, children.
Azithromycin raw material API is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections,ear infections, and sexually transmitted diseases.
Azithromycin Tablets are a macrolide antibacterial drug indicated for the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below.
NOTE:
You should not use Azithromycin if you have ever had jaundice or liver problems when you have previously taken this medicine.
Please do careful before using Azithromycin Dihydrate, Azithromycin Powder liver or kidney disease, a history of Long QT syndrome, a heart rhythm disorder.
Side Effects:
Upon taking Azithromycin, a minority of individuals are susceptible to nausea, diarrhea or vomiting.
| Name of Product | Azithromycin | ||
| Testing Item | Standard | Result | |
| Appearance | A white or almost white crystalline power, odorless and bitter | Complies | |
| Identification
1. IR 2. HPLC |
1. Conforms to the reference spectrum
2. Similar in retention time to the principle peak in the chromatogram obtained with the reference solution |
Complies
Complies |
|
| Crystalline | Should conforms to requirements | Complies | |
| Specific optical rotation | -45°~ -49° | -47° | |
| Water | 4.0%-5.0% | 4.3% | |
| Residue on ignition | ≤0.3% | 0.02% | |
| Residue solvents | 1.Methylene chloride ≤0.06%
2.Acetone ≤0.5% |
1. Not detected
2. 0.1% |
|
| Heavy metals | ≤0.0025% | ＜0.0025% | |
| PH | 9.0-11.0 | 9.9 | |
| Assay (Azithromycin) | 945-1030μg /mg | 962μg /mg | |
| Supplier | Elite Scientific & Meditech Co | www.elitetradebd.com | |
Related products
Macrolides: Azithromycin, clarithromycin, roxithromycin
Quinolones: Ciprofloxacin hydrochloride, ciprofloxacin lactate, ciprofloxacin, ciprofloxacin mesylate, moxifloxacin
Special APIs: Azrendipine, fudosten, mitiglinide, desoxyfluridine, solifenacin, vildagliptin
Veterinary APIs: Ciprofloxacin hydrochloride, enrofloxacin, marbofloxacin, diclazuril, ciprofloxacin
Key pharmaceutical intermediates: Dihydrohomoerythromycin, erythromycin oxime, cyclopropanecarboxylic acid
Supplier in Bangladesh- Elite Scientific & Meditech Co.
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Categories: Pharmaceuticals Raw Materials
